Neurodegeneration: A Case of Arrested Development?

P-101: Effects of Ethanol and Strontium on Growth and Development of Two-Cell Arrested Mouse Embryos

Background: Arresting in a certain step of development like two-cell stage could be one of the reasons of infertility. The aim of this study is evaluating the effects of ethanol and strontium on growth and development of two-cell arrested mouse embryos. Materials and Methods: The females were coupled with male following superovulation. Positive vaginal plug mice were killed 48 hours after hCG i...

The Effects of Ethanol and Strontium on Growth and Development of Two-Cell Arrested Mouse Embryos

P-102: The Effect of Strontium on Growth and Development of Two-Cell Arrested NMRI Mouse Embryos

Background: Decreasing the growth and developmental rate of embryo and arresting in certain step of development like two cell block could be the reason of infertility in some couples referring to fertility and infertility center. The aim of this study is the effect of strontium on growth and development of two-cell arrested NMRI mouse embryo. Materials and Methods: The female mice were coupled ...

Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration

Alzheimer's disease (AD) is characterized by chronic deposition of β-amyloid (Aβ) in the brain, progressive neurodegeneration and consequent cognitive and behavioral deficits that typify the disease. Astrocytes are pivotal in this process because they are activated in the attempt to digest Aβ which starts a neuroinflammatory response that further contributes to neurodegeneration. The intestine ...

P 97: Neurodegeneration Induced by Tau protein

Tau is one of several types of microtubule-associated proteins (MAPs), responsible for the assembly and stability of microtubule networks that is present only in neurons and predominantly localized in axons which its functions are tightly regulated by phosphorylation. Via as yet unknown mechanisms, tau becomes hyperphosphorylated and accompanies with neuronal degeneration, loss of synapses...